sites definition

<enzyme>

<cell biology> An enzyme responsible for producing a species-characteristic methylation pattern on adenine residues in a specific short base sequence in the host cell DNA. The enzyme catalyses the methylation of DNA adenine in the presence of s-adenosyl-l-methionine to form DNA containing 6-methylaminopurine and s-adenosyl-l-homocysteine.

Registry number: EC 2.1.1.72

(12 Dec )

<enzyme>

<cell biology> An enzyme responsible for producing a species-characteristic methylation pattern on cytosine residues in a specific short base sequence in the host cell's DNA. The enzyme catalyses the methylation of DNA cytosine in the presence of s-adenosyl-l-methionine to form s-adenosyl-l-homocysteine and DNA containing 5-methylcytosine.

Registry number: EC 2.1.1.73

(12 Dec )

<cell culture, molecular biology> An in vitro technique in which an alteration is made at a specific site in a DNA molecule, which is then reintroduced into a cell. Various techniques are used, for the cell biologist, a very powerful approach to determining which parts of a protein or nucleotide sequence are critical to function.

This entry appears with permission from the Dictionary of Cell and Molecular Biology

An alteration of the structure of a gene at a specific sequence, usually referring to experimentally produced changes in gene sequence.

<molecular biology> A type of recombination that occurs between two specific short DNA sequences present in the same or in different molecules. An example is the integration and excision of _ prophage.

This entry appears with permission from the Dictionary of Cell and Molecular Biology