nicotinamide-nucleotide adenylyltransferasemedical dictionary

<enzyme>

<cell biology> An enzyme that catalyses reversibly the transfer of the adenylyl moiety of ATP to the phosphoryl group of nmn to form NAD+ and pyrophosphate. The enzyme is found predominantly in the nuclei and catalyses the final reaction in the major pathway for the biosynthesis of NAD in mammals.

Chemical name: ATP:nicotinamide-nucleotide adenylyltransferase

Registry number: EC 2.7.7.1

(12 Dec 1998)