nephritis, interstitialmedical dictionary

Primary or secondary disease of the renal interstitial tissue resulting from arterial, arteriolar, glomerular, or tubular disease which destroys individual nephrons, or from toxic involvement of interstitital cells and tubules due to systemic diseases such as gout, to drug exposure, or to mercury poisoning. Clinically it may be manifested primarily by loss of concentrating capacity, mineral wasting, proteinuria, and abnormal urine sediment. It may be seen in an acute form, particularly after specific bacterial infection, and may result in acute papillary necrosis. More commonly, the process is a chronic one with progressive renal atrophy and diminution of renal function.

(12 Dec 1998)

nephritis, nephritis gravidarum, nephritis, hereditary < Prev | Next > nephritogenic, nephro-, nephroblastema

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