dictionary help| von Recklinghausen's disease | medical dictionary |
<disease>
A rare genetic disorder which affects the cell growth of nerve tissue. Individuals have multiple cutaneous and subcutaneous tumours which appear in late childhood.
Clinical features include medium-brown, flat discolourations to the skin, known as cafe-au-lait spots.
Secondary hypertension may develop from renal artery stenosis, pheochromocytoma or coarctation of the aorta.
Inheritance: autosomal dominant.
(04 Nov 1997)
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