| vinblastine sulfate | medical dictionary |
A dimeric alkaloid obtained from Vinca rosea. It arrests mitosis in metaphase (although vincristine is more active in this respect) and exhibits greater antimetabolic activity than does vincristine; used in the treatment of Hodgkin's disease, choriocarcinoma, acute and chronic leukaemias, and other neoplastic diseases; blocks microtubule assembly.
Synonyms: vincaleucoblastine.
(05 Mar 2000)
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