uracil-DNA glycosidasemedical dictionary

<enzyme>

<cell biology> Catalyses hydrolysis of n-glycosidic bond of damaged nucleotide residues to give free uracil and partly depyrimidinated DNA of unaltered chain length; does not cleave phosphodiester bonds; a DNA repair enzyme

Registry number: EC 3.2.2.-

Synonyms: ura-DNA glycosidase, uracil-DNA glycosylase, uracil n-glycosidase, ura-DNA glycosylase, uracil n-glycosylase

(26 Jun 1999)