N(2)-(1-(n(2)-l-threonyl)-l-lysyl)-l-prolyl)-l-arginine. A tetrapeptide produced in the spleen by enzymatic cleavage of a leukophilic gamma-globulin. It stimulates the phagocytic activity of blood polymorphonuclear leukocytes and neutrophils in particular. The peptide is located in the fd fragment of the gamma-globulin molecule.
(12 Dec 1998)
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