<computer hardware> The body or base layer of an integrated circuit, onto which other layers are deposited to form the circuit. The substrate is usually Silicon, though Sapphire is used for certain applications, particularly military, where radiation resistance is important. The substrate is originally part of the wafer from which the die is cut. It is used as the electrical ground for the circuit.

(01 Feb 1996)

<chemistry> A substance upon which an enzyme acts.

Origin: L. Stratum = layer

(11 Mar 2008)