seronegativemedical dictionary

Lacking an antibody of a specific type in serum; used to mean absence of prior infection with a specific agent (e.g., rubella virus), disappearance of antibodies after treatment of a disease (e.g., syphilis), or absence of antibody usually found in a given syndrome (e.g., rheumatoid arthritis without rheumatoid factor).

(05 Mar 2000)