<biochemistry, enzyme, molecular biology> Widely distributed type of enzyme that cleaves RNA. May act as endonucleases or exonucleases depending upon the type of enzyme. Generally recognise target by tertiary structure rather than sequence.
Ribonuclease T is an endonuclease that removes the terminal AMP from the 3' CCA end of a nonaminoacylated tRNA. Ribonuclease T1 cleaves RNA specifically at guanosine residues. Ribonuclease TIII cleaves double stranded regions of RNA molecules.
(23 Aug 1998)
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