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<oncogene>

One of a family of oncogenes, first identified as transforming genes of Harvey and Kirsten murine sarcoma viruses. (Name from rat sarcoma because Harvey virus, though a mouse virus, obtained its transforming gene during passage in a rat). Transforming protein coded is p21ras, a GTP-binding protein with GTPase activity, that resembles regulatory G-proteins.

This entry appears with permission from the Dictionary of Cell and Molecular Biology

(11 Mar 2008)

rareripe, rare species, RARP, RAS < Prev | Next > rascaldom, rascaless, rasceta, rash

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