The antigenic specificites defined by the unique sequences (idiotopes) of the antigen combining site. Thus anti-idiotype antibodies combine with those specific sequences, may block immunological reactions and may resemble the epitope to which the first antibody reacts.

This entry appears with permission from the Dictionary of Cell and Molecular Biology

(11 Mar 2008)

idiotroph, idiotrophic, idiotropic, idiot-savant < Prev | Next > idiotype antibody, idiotype autoantibody

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