dictionary help| pyroglutamic acid --> 5-oxoproline | medical dictionary |
A keto derivative of proline that is formed nonenzymatically from glutamate, glutamine, and gamma-glutamylated peptides; it is also produced by the action of gamma-glutamylcyclotransferase; elevated levels of 5-oxoproline are often associated with problems of glutamine or glutathione metabolism.
Synonyms: 5-pyrrolidone-2-carboxylic acid, pyroglutamic acid, pyrrolidone-5-carboxylate.
(05 Mar 2000)
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase, 5-oxoprolinase < Prev | Next > 5-oxoprolinuria, 5'-phosphate-polyribonucleotide kinase
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