proto-oncogene proteins c-rafmedical dictionary

<enzyme>

<cell biology> A class of serine-threonine kinases involved in cellular signal transduction. Included in this class are the proto-oncogene proteins mil and raf. Raf is a component of a signal transduction pathway leading to increased gene expression through the c-jun DNA binding site, ap1.

Registry number: EC 2.7.10.-

(12 Dec 1998)