See: PrP, Gerstmann-Straussler-Scheinker syndrome. Suggested as the causative agents of several infectious diseases such as scrapie (in sheep), kuru and Creutzfeld Jakob disease in man. Prions (proteinaceous infective particles) apparently contain no nucleic acid. The 27 kD protein of scrapie is related to a normal cell protein and may possibly cause its over production.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
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