<chemical>

The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor.

Pharmacological action: analgesics, opioid, anaesthesia adjuvants, narcotic antagonists, narcotics.

Chemical name: 2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-, (2alpha,6alpha,11R*)-

(12 Dec 1998)