5-(2-aminoethyl)-1,2,4-benzenetriol. A catecholamine, vasoactive neurotoxic compound which depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. The compound has been used clinically for purging of neuroblastoma cells prior to autologous bone marrow transplantation. When used by subconjunctival injection it produces reversible chemical sympathectomy in glaucoma.

Pharmacological action: adrenergic agents, sympatholytics.

Chemical name: 1,2,4-Benzenetriol, 5-(2-aminoethyl)-

(12 Dec 1998)

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