osteodysplastymedical dictionary

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A generalised skeletal dysplasia with prominent forehead and small mandible; radiographically, there are irregular ribbon-like constrictions of the ribs and tubular bones; probably autosomal dominant inheritance. There are arguably two forms, autosomal recessive and X-linked.

Synonyms: Melnick-Needles syndrome.

Origin: osteo-+ G. Dys-, bad, + plastos, formed

(05 Mar 2000)