|orotic acid||medical dictionary|
Intermediate in the de novo synthesis of pyrimidines. Linked glycosidically to ribose 5' phosphate, orotate forms the pyrimidine nucleotide orotidylate, that on decarboxylation at position 5 of the pyrimidine ring yields the major nucleotide uridylate (uridine 5' phosphate).
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
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