ordered -->
ordered mechanism
medical dictionary

A scheme for substrate binding and product release for multisubstrate enzymes; for a two-substrate two-product enzyme with an ordered mechanism, one particular substrate has to bind to the enzyme first followed by the other substrate; chemistry then occurs, products are formed and are released from the enzyme in a distinct order. More complex ordered schemes exist for enzymes having more than two substrates. Some of the dehydrogenases have such a mechanism.

Synonyms: ordered.

(05 Mar 2000)