oestrogen antagonistmedical dictionary

<pharmacology> A drug or compound which inhibit or antagonise the action or biosynthesis of oestrogen.

Tamoxifen also has agonist or stimulatory actions as well as blocking effects. There are also selective oestrogen-receptor modulators (SERMs). For example, raloxifene (trade name Evista) is classified as a SERM because it prevents bone loss (like oestrogen) and lowers serum cholesterol (like oestrogen) but (unlike oestrogen) does not stimulate the endometrial lining of the uterus.

American spelling: estrogen antagonist

(12 May 2002)

oestrian, oestrids, oestriol, oestrogen < Prev | Next > oestrogenic, oestrogenic hormone, oestrogenism

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