odouratism -->
medical dictionary

An experimental disease in rats, swine, turkeys, and other animals fed the seeds of certain species of Lathyrus (e.g., L. Odouratus, sweet pea), or such nitriles as aminoacetonitrile or beta-aminopropionitrile; the chief pathologic changes occur in connective tissue structures, as follows: 1) fibroblastic, chondroblastic, and osteoblastic proliferative changes in the periosteum; 2) degeneration, necrosis, and atypical proliferation of epiphysial cartilages; 3) an increase in adipose tissue of the bone marrow; 4) sometimes proliferation of synovial membranes; 5) relatively large foci of extensive destruction of elastic fibres in the aorta, especially in the thoracic aorta.

Origin: osteo-+ lathyrism

(05 Mar 2000)