neutralizationmedical dictionary

1. The act or process of neutralising, or the state of being neutralized.

2. <chemistry> The act or process by which an acid and a base are combined in such proportions that the resulting compound is neutral. See Neutral.

Origin: Cf. F. Neutralisation.

(01 Mar 1998)

neutralization platemedical dictionary

A metal plate used for the internal fixation of a long bone fracture to neutralise the forces producing displacement.

(05 Mar 2000)

neutralization testmedical dictionary

Preferred term: protection test

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neutralization testsmedical dictionary

Titration of an antiserum by testing a series of dilutions of virus or immune serum to a given end-point, which is generally the dilution at which tissue cultures inoculated with the serum-virus mixtures demonstrate cytopathology (cpe) or the dilution at which 50% of test animals injected with serum-virus mixtures show infectivity (id50) or die (ld50).

(12 Dec 1998)

1. To render neutral; to reduce to a state of neutrality. "So here I am neutralized again." (Sir W. Scott)

2. <chemistry> To render inert or imperceptible the peculiar affinities of, as a chemical substance; to destroy the effect of; as, to neutralize an acid with a base.

3. To destroy the peculiar or opposite dispositions of; to reduce to a state of indifference inefficience; to counteract; as, to neutralize parties in government; to neutralize efforts, opposition, etc. "Counter citations that neutralize each other." (E. Everett)

Origin: Cf. F. Neutraliser.

(01 Mar 1998)

neutralizing antibodymedical dictionary

A form of antibody that reacts with an infectious agent (usually a virus) and destroys or inhibits its infectivity and virulence; may be demonstrated by means of mixing serum with the suspension of infectious agent, and then injecting the mixture into animals or cell cultures that are susceptible to the agent in question.

(05 Mar 2000)