<clinical sign>

<clinical examination> A general term denoting functional disturbances and/or pathological changes in the peripheral nervous system. If the involvement is in one nerve it is called mononeuropathy, in several nerves, mononeuropathy multiplex, if diffuse and bilateral, polyneuropathy.

The aetiology may be known for example arsenical neuropathy, diabetic neuropathy, ischaemic neuropathy, traumatic neuropathy) or unknown. Encephalopathy and myelopathy are corresponding terms relating to involvement of the brain and spinal cord, respectively. The term is also used to designate noninflammatory lesions in the peripheral nervous system, in contrast to inflammatory lesions (neuritis).

Origin: Gr. Pathos = disease

(11 Mar 2008)