<chemical>

1,3-dihydro-1-methyl-2h-imidazole-2-thione. A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.

Pharmacological action: antithyroid agents.

Chemical name: 2H-Imidazole-2-thione, 1,3-dihydro-1-methyl-

(12 Dec 1998)