Waldenstrom's macroglobulinaemia, macroglobulinaemia occurring in elderly persons, characterised by proliferation of cells resembling lymphocytes or plasma cells in the bone marrow, anaemia, increased sedimentation rate, and hyperglobulinaemia with a narrow peak in gamma-globulin or b2-globulin at about 19 S units. The spleen, liver, or lymph nodes are often enlarged and there is frequently purpura or mucosal bleeding.
American spelling: macroglobulinemia
(05 Mar 2000)
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