hypertensive arteriosclerosismedical dictionary

Progressive increase in muscle and elastic tissue of arterial walls, resulting from hypertension; in longstanding hypertension, elastic tissue forms numerous concentric layers in the intima and there is replacement of muscle by collagen fibres and hyaline thickening of the intima of arterioles; such changes can develop with increasing age in the absence of hypertension and may then be referred to as senile arteriosclerosis.

(05 Mar 2000)