hydroxykynureninuriamedical dictionary

An abnormality in tryptophan metabolism, probably due to a defect in kynureninase, characterised by mild mental retardation, migraine-like headaches, and urinary excretion of large amounts of kynurenine, kynurenine-3-monooxygenase, and xanthurenic acid; autosomal recessive inheritance.

(05 Mar 2000)