haemophilia Amedical dictionary

<haematology> A sex-linked genetic disease affecting males that results from a deficiency of clotting factor VIII, a protein factor that is required for normal blood coagulation.

Symptoms include easy bruising, bleeding gums, nosebleeds and bleeding into muscle tissue (haematoma) or a joint space (haemarthrosis).

Treatment includes the infusion of factor VIII concentrate intravenously to restore this essential factor and normalize blood coagulation.

Inheritance: sex-linked.

American spelling: hemophilia A

(27 Sep 1997)