glutathione synthasemedical dictionary

<enzyme>

<cell biology> One of the enzymes active in the gamma-glutamyl cycle. It catalyses the synthesis of glutathione from gamma-glutamylcysteine and glycine in the presence of ATP with the formation of ADP and orthophosphate.

Chemical name: gamma-L-Glutamyl-L-cysteine:glycine ligase (ADP-forming)

Registry number: EC 6.3.2.3

(12 Dec 1998)