glutamate dehydrogenasesmedical dictionary

Enzymes that catalyze the reaction of l-glutamate, H2O, and NAD+ (or NADP+ in some cases) producing alpha-ketoglutarate (2-oxoglutarate), ammonia, and NADH; in mammals, this is the prime contributor to oxidative deamination.

Synonyms: glutamic acid dehydrogenases.

(05 Mar 2000)