dictionary help| glutamate decarboxylase | medical dictionary |
<enzyme>
<cell biology> A pyridoxal-phosphate protein that catalyses the alpha-decarboxylation of l-glutamic acid to form gamma-aminobutyric acid and carbon dioxide. The enzyme is found in bacteria and in invertebrate and vertebrate nervous systems. It is the rate-limiting enzyme in determining gaba levels in normal nervous tissues. The brain enzyme also acts on l-cysteate, l-cysteine sulfinate, and l-aspartate.
Chemical name: L-Glutamate-1-carboxy-lyase
Registry number: EC 4.1.1.15
(12 Dec 1998)
glutamate aminotransferase, glutamate-ammonia ligase, glutamate-cysteine ligase < Prev | Next > glutamate dehydrogenase, glutamate dehydrogenase (NADP+)
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