gene conversionmedical dictionary

<molecular biology> A phenomenon in which alleles are segregated in a 3:1 not 2:2 ratio in meiosis. May be a result of DNA polymerase switching templates and copying from the other homologous sequence or a result of mismatch repair (nucleotides being removed from one strand and replaced by repair synthesis using the other strand as template).

This entry appears with permission from the Dictionary of Cell and Molecular Biology

(11 Mar 2008)

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