|gene amplification||medical dictionary|
<molecular biology> Selective replication of DNA sequence within a cell, producing multiple extra copies of that sequence. The best known example occurs during the maturation of the oocyte of Xenopus, where the set (normally 500 copies) of ribosomal RNA genes is replicated some 4,000 times to give about 2 million copies.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
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