<oncogene>

A proto-oncogene that causes leukaemias in chickens.

It is found in E26 transforming retrovirus (v-ets) of chickens and encodes a nuclear protein that can bind DNA and regulates the initiation of transcription from a range of cellular and viral promoter and enhancer elements which may help activate and proliferate T lymphocyte cells. There is some interaction between ets and AP1.

(24 Mar 1998)

E Towne, etozolin, ETP, etretinate, ETRN < Prev | Next > ETSI, -ette, etter pike

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