dipyrimidine photolyase -->
deoxyribodipyrimidine photolyase
medical dictionary

<enzyme>

<cell biology> An enzyme in yeast that is activated by light, whereupon it can reverse a previous photochemical reaction by cleaving the cyclobutane ring of the thymine dimer.

It catalyses the reactivation by light of UV-irradiated DNA and cleaves two carbon-carbon bonds in pyrimidine dimers in DNA.

Synonyms: dipyrimidine photolyase, photoreactivating enzyme.

Chemical name: Deoxyribocyclobutadipyrimidine pyrimidine-lyase

Registry number: EC 4.1.99.3

(21 Jun 2000)