dictionary help| diphtheria toxin | medical dictionary |
<protein>
An ab exotoxin (62 kD) coded by _ corynephage of virulent Corynebacterium diphtheriae strains (that can produce a repressor of toxin production). The B subunit binds to receptors on the surface of the target cell and facilitates the entry of the enzymically active A subunit (21 kD) that ADP ribosylates elongation factor 2, thereby halting mRNA translation.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
diphtheria antitoxin unit, diphtherial, diphtheria-tetanus-pertussis vaccine < Prev | Next > diphtheria toxoid, diphtheric, diphtheritic
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