dictionary help| diacylglycerol | medical dictionary |
Glycerol substituted on the 1 and 2 hydroxyl groups with long chain fatty acyl residues. DAG is a normal intermediate in the biosynthesis of phosphatidyl phospholipids and is released from them by phospholipase C activity. DAG from phosphatidyl inositol polyphosphates is important in signal transduction. Elevated levels of DAG in membranes activate protein kinase C by stabilising its catalytically active complex with membrane bound phosphatidyl serine and calcium.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
diacrisis, diacritic, diacritical, diactinic < Prev | Next > diacylglycerol cholinephosphotransferase, diacylglycerol kinase
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