determinant group -->
antigenic determinant
medical dictionary

That part of an antigenic molecule against which a particular immune response is directed. For instance a tetra to penta peptide sequence in a protein, a tri to penta glycoside sequence in a polysaccharide.

In the animal most antigens will present several or even many antigenic determinants simultaneously.

See: hapten.

This entry appears with permission from the Dictionary of Cell and Molecular Biology

(22 Feb 2008)