cytochrome p-450medical dictionary

<biochemistry> Enzymes of the electron transport chain that are pigmented by virtue of their haem prosthetic groups.

They are highly conserved isozymes which are key components of the mixed-function oxidase system responsible for the biotransformation of many foreign compounds to mutagens and carcinogens.

Most mammals have several distantly related phenobarbital-inducible gene subfamilies.

(21 Jun 2000)