consumption coagulopathymedical dictionary

<haematology> A disorder that includes accelerated platelet consumption with coagulation factor depletion (prolongation of PT and PTT) and stimulation of fibrinolysis (generation of fibrin split products).

Disseminated intravascular coagulation can be caused by severe bacterial infections (sepsis), extensive burns, trauma, retained dead foetus, heatstroke, mismatched blood transfusion, metastatic cancer and some forms of leukaemia. Manifests with severe bleeding and bruising.

Origin: Gr. Pathos = disease

(27 Sep 1997)