dictionary help| congenital virilizing adrenal hyperplasia | medical dictionary |
A series of inherited inborn errors of metabolism with hyperplasia of the adrenal cortex and overproduction of virilizing hormones. Most common forms are due to partial or complete 21-hydroxylase deficiency, leading to increased ACTH production by the pituitary, stimulating adrenal growth and function. Severe form is characterised by salt-losing state.
(05 Mar 2000)
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