congenital dyserythropoietic anaemiamedical dictionary

A group of autosomal recessive anaemia's characterised by ineffective erythropoiesis, bone marrow erythroblastic multinuclearity, and secondary haemochromatosis. Three types are described:

Type I, macrocytic, megaloblastic anaemia with erythroblastic internuclear chromatin bridges, type II,, normoblastic anaemia with multinucleated erythroblasts, type III, macrocytic anaemia with erythroblastic multinuclearity and gigantoblasts.

American spelling: congenital dyserythropoietic anemia

(05 Mar 2000)