<cell biology> Protein composed of 3 heavy chains (180 kD) and 3 light chains (34 and 36 kD), that forms the basketwork of triskelions around a coated vesicle. There are two genes for light chains, each of which can generate two distinct transcripts by tissue specific alternative splicing.

This entry appears with permission from the Dictionary of Cell and Molecular Biology

(11 Mar 2008)