calcium channel-blocker -->
calcium channel antagonist
medical dictionary

<pharmacology> A class of drugs that act by selective inhibition of calcium ion influx through or across cell membranes or on the release and binding of calcium in intracellular pools.

Calcium channel blockers are used primarily in the treatment of certain heart conditions and stroke. As they are inducers of vascular and other smooth muscle relaxation, they are also used in the treatment of hypertension and cerebrovascular spasms, as myocardial protective agents, and in the relaxation of uterine spasms.

Synonyms: calcium antagonist, calcium channel-blocker, slow channel-blocking agent.

(12 May 2002)