band III proteinmedical dictionary


A 90 kD protein embedded in the surface of the human erythrocyte membrane, identified as the major anion transport/exchange protein. When the red blood cell is in the lungs, brings chlorine ion into the cell in exchange for bicarbonate.

Analogous proteins exist in other erythrocytes. A dimeric transmembrane glycoprotein, with binding sites for many cytolasmic proteins, including ankyrin, on its cytoplasmic domain.

This entry appears with permission from the Dictionary of Cell and Molecular Biology

(11 Mar 2008)

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