|area under curve||medical dictionary|
It is frequently used in clinical pharmacology where the AUC from serum levels can be interpreted as the total uptake of whatever has been administered. , producing a standard shape curve. It is a means of comparing the bioavailability of a drug.
A measure of how much of a drug reaches the bloodstream in a set period of time, usually 24 hours. The AUC is then calculated by plotting the concentration following a single dose of a drug against time at various points during a 24-hour or longer period and then measuring the area under the curve between 0 and 24 hours.
(12 Jan 2009)
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