antigen-presenting cellmedical dictionary

<immunology> An immunocompetent cell that mediates the cellular immune response by presenting antigens or mitogens bound to MHC Class I or Class II molecules, which stimulate T-cell activation.

Includes macrophages, endothelial cells, dendritic cells and Langerhans cells in the skin.

See: MHC restriction, histocompatibility antigens.

(18 Nov 2007)