Sanger's reagent -->
fluoro-2,4-dinitrobenzene
medical dictionary

A reagent used to combine with the free NH2 group of the NH2-terminal amino acid residue in a peptide, thus marking this residue; the combined forms are known as DNP-proteins, Dnp-aminoacyl, etc., the fluorine having been replaced to leave a dinitrophenyl residue (DNP, Dnp, or N2Ph-) attached to the NH2 group.

Synonyms: Sanger's reagent.

Acronym: FDNB

(05 Mar 2000)