SSRI -->
selective serotonin reuptake inhibitor
medical dictionary

<pharmacology> This is a class of drug that are used as antidepressants.

Functionally, they increase the levels of serotonin in the body. These drugs can be dangerous if they are mixed with other drugs such as other antidepressants, illicit drugs (LSD, cocaine, methamphetamine), some antihistamines (Seldane, Histmanal), some antibiotics, and calcium channel blockers.

Side effects include lethargy, confusion, flushing, sweating and muscle spasms. Overdose can cause damage to red blood cells, breathing problems and kidney damage.

Examples include: Prozac, Zoloft and Paxil.

Acronym: SSRI

(12 Jan 1998)